Ketamine can cut depression, suicidality rapidly

Ketamine can cut depression, suicidality rapidly

Esketamine could be an important treatment to bridge the gap as it can help in the rapid treatment compared to the delayed effects of most common antidepressants, which take four to six weeks to become fully effective, said Jaskaran B. Singh, from the Janssen Research & Development in San Diego, US.

Meanwhile, due to potential abuse of Ketamine, scientists noted that more research is necessary to protect users.

"The interesting United States study confirmed the findings from successful studies into intravenous ketamine", said Dr James Stone from Royal College of Psychiatrists, "The main reason for its significance is because this is being developed by a drug company and it's potentially quite likely that this medication might become available as a treatment available on the NHS for depression".

"In just a matter of hours" participants in the ketamine test group and their doctors "measured a significant improvement in symptoms of patients classed as being at high risk of suicide", says The Independent.

The research team stated the results of the phase 2 study provide a strong case for the nasal spray esketamine to be used as a fast-acting and effective treatment for depressive symptoms in patients assessed to be at imminent risk for suicide.

All the participants received treatment throughout the trial and researchers recorded their observations after four hours, 24 hours, and 25 days from the time the anti-depressants were given.

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According to the authors of the study there were no reports of abuse of the drug during the trial.

During the study, 68 people with suicidal thoughts have been treated with anti-depressants. Patients in one group received the standard treatment along with ketamine in the form of a nasal spray known as esketamine.

"The main reason for its significance is because this is being developed by a drug company and it's potentially quite likely that this medication might become available as a treatment available on the NHS for depression", he said.

Dr Stone did warn, however, that far bigger studies are needed to look out for any rare side-effects of using the drug, either nasally or intravenously.

Findings were published from the first study by a drug company to examine ketamine as a treatment option for depression. This is already happening in private clinics in the USA and the UK.

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