Vaccine against HIV on the horizon after 'promising' drug test results

AIDS activists light a group of candles placed in the shape of a red ribbon during an event marking World AIDS Day in Manila

"We have to acknowledge that developing an HIV vaccine is an unprecedented challenge, and we will not know for sure whether this vaccine will protect humans".

"This is only the fifth HIV vaccine concept that will be tested for efficacy in humans in the 35+ year history of the global HIV epidemic", Barouch added. "Obviously, the search for an HIV vaccine is very elusive". The potential development of this HIV vaccine, which is entirely safe for humans, is quite promising, and the next phase would be to test it on 2,600 women in southern Africa.

This study was supported by Janssen Vaccines & Prevention BV and the NIH, the Ragon Institute of MGH, MIT and Harvard, and a cooperative agreement between the Henry M Jackson Foundation for the Advancement of Military Medicine and the US Department of Defense.

The team created a mosaic-style vaccine by taking parts from different HIV viruses and combining them. The researchers found that every person who received the vaccine produced some kind of anti-HIV immune response, with almost 80 percent producing more advanced responses.

Scientists use these initial phases of clinical trials to determine the best dosage to use and to see whether a vaccine is safe.

A vaccine against HIV affected people.

With 1.8 million new cases of human immunodeficiency virus every year, according to United Nations estimates, and nearly 37 million people living with HIV worldwide, the quest for a vaccine has been urgent - and extremely hard.

England fans slammed by police as 'disgraceful' after win
A group of England fans smashed the windscreen of an ambulance auto as celebrations got out of hand at London's Borough Market. Czechoslovakia and Yugoslavia advanced to the semi-finals in 1962 without a player aged 26 or over scoring for them.

Scientists have developed a new vaccine that can safely and effectively elicit immune response against a wide variety of HIV strains, an advance which may help prevent the deadly infection in the future.

Scientists also carried out a parallel study where they gave rhesus monkeys the vaccine to protect them from getting simian-human immunodeficiency virus - a virus similar to HIV that infects monkeys. Though the vaccine triggered a response in the immune system of the people who took it, it is not clear if this would be enough to fight off the virus and prevent infection. The participants were randomly assigned one of seven combinations of a vaccine, while one group was given a placebo.

To do this, they recruited 393 healthy, HIV-uninfected adults (aged 18 to 50 years) between February and October 2015.

It also protected some monkeys from a virus that is similar to HIV.

We have no evidence so far that it will actually work in the field, so it's important to be cautious interpreting these early results. Scientists must await the results of this trial find out whether the vaccine cannot only provoke an immune response, but actively protect against HIV.

"The road to the clinic is still unpredictable since the exact mode of action in humans is still unknown and the 67 percent protection in monkeys might not be replicable in humans", said George Williams Mbogo from the Burnet Institute in Australia, who wasn't involved in the study.

Related news:

Hot News

isis-killer-beheading-video-story-top Egypt jails tourist for Facebook post
Jul 09, 2018 - 21:32
Mazbouh fiercely criticized the way she had been treated, claiming she was "harassed by taxi drivers and men in the street". Mona's lawyer Imad Kamal said that ten years ago she underwent brain surgery, then it's hard for her to cope with anger.

isis-killer-beheading-video-story-top Wilshere leaves Arsenal for London rival West Ham
Jul 09, 2018 - 21:04
The London club are also keen on the Borussia Dortmund and Ukraine forward, Andriy Yarmolenko, with a fee of around £18m mooted. West Ham are reportedly set to complete a club record deal for Lazio winger Felipe Anderson .

isis-killer-beheading-video-story-top Amazon Prime Day 2018: Best Things to Buy
Jul 09, 2018 - 20:28
Amazon Prime Day is almost upon us, marking your best chance to nab a bargain in the long summer months before Black Friday . Amazon Prime Day is a yearly shopping event in which Prime subscribers have access to deals across Amazon's retail site.

"Sacha Baron Cohen Stars in 'Who Is America?" for Showtime
Jul 09, 2018 - 20:23
It is with heavy hearts and sober minds that we must report Sacha Baron Cohen is back on his bullshit. Behind the elaborate setup is a genuine quest for the truth about people, places and politics.

isis-killer-beheading-video-story-top Is Meghan Markle Growing Out Her Signature Hair Style?
Jul 09, 2018 - 20:13
She also wore a Givenchy creation during her first solo day out with the Queen when the two visited Cheshire. Do not cut, copy or lift any content from this website without our consent.

isis-killer-beheading-video-story-top "I'll show him!" - France's Giroud aims to prove Thierry Henry wrong
Jul 09, 2018 - 20:09
The outing against Brazil though, has to rank as one of his best in national colours so far, if not the best. Both have played key roles in helping their teams to the last four.

isis-killer-beheading-video-story-top Police arrest principal, 5 others in rape of student
Jul 09, 2018 - 20:08
Four students of the school, who were also allegedly involved in the incident, were sent to the remand home as they are juveniles. Woman police SHO Indra Rani said the survivor would be produced before a judicial magistrate on Saturday to record her statement.

isis-killer-beheading-video-story-top Alonso denies any role in McLaren management changes
Jul 09, 2018 - 19:08
McLaren team boss Eric Boullier resigned from his post on Thursday and leaves a question mark surrounding team structure and Fernando Alonso's future.

isis-killer-beheading-video-story-top Take a selfie with God and I will resign: President Rodrigo Duterte
Jul 09, 2018 - 18:32
Roque said he met with around 18 bishops on Sunday evening in a dinner hosted by former President and now Pampanga Rep. Duterte refused to apologize for his comments, saying that "your God is not my God because your God is stupid ".

isis-killer-beheading-video-story-top Dominic Raab replaces David Davis as new Brexit secretary
Jul 09, 2018 - 17:51
British Brexit Secretary David Davis has resigned from Government, effective immediately, United Kingdom media reports say. Denying that he wanted to unseat the prime minister, he said he would now "argue for being as firm as possible".

isis-killer-beheading-video-story-top Craig Dawson hands in West Bromwich Albion transfer request
Jul 09, 2018 - 17:44
Johnstone spent last season on loan at Aston Villa and has also had spells at Scunthorpe, Walsall, Doncaster, Yeovil and Preston. WEST BROMWICH ALBION have signed goalkeeper Sam Johnstone from Manchester United on a four-year deal.

isis-killer-beheading-video-story-top Starbucks is eliminating plastic straws from all stores
Jul 09, 2018 - 17:41
The changes will help Starbucks ( SBUX ) eliminate more than 1 billion plastic straws per year, the company said . Starbucks said that it is the largest food and beverage retailer to have promised to get rid of plastic straws.

isis-killer-beheading-video-story-top Robin Wright speaks about ex-'House of Cards' star Spacey
Jul 09, 2018 - 17:39
Last week, Guy Pearce claimed that disgraced actor Kevin Spacey behaved inappropriately with him on set of the 1997 movie L.A. Spacey also came out as gay in the same statement, much to the chagrin of many members of the LGBT community .

isis-killer-beheading-video-story-top Hamilton fastest in FP3, huge crash for Hartley
Jul 09, 2018 - 16:41
Luckily, the 28-year-old was able to walk away from the wreckage and gave fans a wave on his way to receive medical attention. Gasly's early time, prior to Hartley's failure, left him 19th on the leaderboard.

isis-killer-beheading-video-story-top Kylie Jenner reveals on Instagram she removed lip filler
Jul 09, 2018 - 16:39
Another stated: "You look awesome, fresh , young and handsome with your natural self". "I love that", one fan wrote. Simon Ourian, a cosmetic surgeon who worked on Jenner, told Page Six in September.